Can't be done really...
Large capacity cartridges like the .300 Wby need every inch of barrel length they can get to make the most of the slow burning magnum rifle powders used in them. Slower buring powders+long barrels=incresed velocities with comparativley tame chamber pressures.
You could theoretically use powders with a faster burn rate, but the chamber pressure will go up way faster than you could reach usuable velocities.
With short barreled guns, especially in handguns... the name of the game is cartridges efficiency.... getting the most out of the limited barrel length using cartridges with shorter, fatter powder collums to give better ignition and burn. Allowing the powder to burn as completle as possible before exiting the muzzle.
Trust me this one will probably be more wrist twisting, thundering fun then 99.9% of people would care for.
